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一项计算机定制决策辅助工具改善前列腺癌筛查决策的随机试验:来自 Take the Wheel 试验的结果。

A randomized trial of a computer-tailored decision aid to improve prostate cancer screening decisions: results from the Take the Wheel trial.

机构信息

Dana-Farber Cancer Institute, Harvard MedicalSchool, School of Public Health, Boston, Massachusetts, USA.

出版信息

Cancer Epidemiol Biomarkers Prev. 2010 Sep;19(9):2172-86. doi: 10.1158/1055-9965.EPI-09-0410. Epub 2010 Aug 17.

Abstract

OBJECTIVE

To evaluate a decision aid (DA) designed to promote informed decision making for prostate cancer screening.

METHODS

Twelve work sites were randomly assigned to an intervention or nonintervention comparison condition. Intervention sites received access to a computer-tailored DA at the workplace. Male employees age 45 years and above (n = 625) completed surveys at baseline and at 3-month follow-up, documenting aspects of informed decision making.

RESULTS

Using an intention-to-treat analysis, men in the intervention group were significantly more likely to have made a screening decision and to have improved knowledge without increased decisional conflict, relative to men in the comparison group. These changes were observed despite the fact that only 30% of men in intervention sites used the DA. Among DA users, similar improvements were observed, although the magnitudes of changes were substantially greater, and significant improvements in decision self-efficacy were observed.

CONCLUSIONS

A DA offered in the workplace promoted decision making, improved knowledge, and increased decision self-efficacy among users, without increasing decisional conflict. However, participation was suboptimal, suggesting that better methods for engaging men in workplace interventions are needed. IMPACT STATEMENT: This trial shows the efficacy of a computer-tailored DA in promoting informed decisions about prostate cancer screening. The DA was delivered through work sites, thereby providing access to resources required to participate in informed decision making without requiring a medical appointment. However, participation rates were suboptimal, and additional strategies for engaging men are needed.

摘要

目的

评估旨在促进前列腺癌筛查决策知情的决策辅助工具(DA)。

方法

12 个工作场所随机分配到干预组或非干预对照组。干预组在工作场所获得计算机定制的 DA。45 岁及以上的男性员工(n=625)在基线和 3 个月随访时完成调查,记录知情决策的各个方面。

结果

采用意向治疗分析,与对照组相比,干预组的男性更有可能做出筛查决策,并且在知识提高的同时,决策冲突没有增加。尽管干预组中只有 30%的男性使用了 DA,但仍观察到这些变化。在 DA 用户中,也观察到了类似的改善,尽管变化幅度更大,而且观察到决策自我效能感显著提高。

结论

在工作场所提供的 DA 促进了决策制定,提高了知识水平,并提高了用户的决策自我效能感,而不会增加决策冲突。然而,参与率不理想,表明需要更好的方法来吸引男性参与工作场所干预。

影响说明

这项试验表明,计算机定制的 DA 在促进关于前列腺癌筛查的知情决策方面是有效的。DA 通过工作场所提供,从而在不要求预约医疗的情况下,为参与知情决策提供所需的资源。然而,参与率不理想,需要采取其他策略来吸引男性。

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