Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill School of Medicine, 3010 Old Clinic Building, CB# 7516, Chapel Hill, NC 27599-7516, USA.
Arch Gynecol Obstet. 2011 Aug;284(2):303-6. doi: 10.1007/s00404-010-1647-2. Epub 2010 Aug 18.
Acute lymphocytic leukemia (ALL) is a rare occurrence in pregnancy and can be rapidly fatal if left untreated. The need for immediate treatment of ALL, coupled with the maternal-fetal risks from the chemotherapy regimen render a therapeutic dilemma in pregnant women with ALL. We report a case of ALL diagnosed in the 24th week of pregnancy to outline our management strategy, to demonstrate the feasibility of treatment with multi-agent chemotherapy, and to provide a review of the literature.
急性淋巴细胞白血病(ALL)在妊娠中较为罕见,如果不加以治疗,可能会迅速致命。ALL 需要立即治疗,而化疗方案对母婴的风险使得 ALL 孕妇面临治疗困境。我们报告了 1 例在妊娠 24 周时诊断出的 ALL 病例,以阐述我们的治疗策略,展示多药物化疗治疗的可行性,并对文献进行回顾。