接受全胃切除术的胃癌患者的临床病理特征。

Clinicopathologic features of gastric carcinoma patients who undergo a total gastrectomy.

作者信息

Joo Jae Kyoon, Kim Ho Gun, Ryu Seong Yeob, Lee Jae Hyuk, Kim Dong Yi

机构信息

Division of Gastroenterologic Surgery, Department of Surgery, Chonnam National University Medical School, Gwangju, Korea.

出版信息

Int Surg. 2010 Apr-Jun;95(2):147-52.

PMID:20718322

Abstract

Epidemiologic studies show a continued increase in the number of total gastrectomies (TGs) performed. We compared the clinicopathologic features and outcomes of patients who underwent a TG to those who received a distal gastrectomy (DG). Cases of 696 patients treated with TG were reviewed retrospectively. Multivariate analysis showed that age, tumor size, presence of serosal invasion, lymph node metastasis, and curability were significant prognostic factors for survival of patients who had a TG. The 5-year survival rate of patients who underwent a TG (39.5%) was lower than that of those receiving a DG (56.1%; P < 0.001). Patients who underwent a TG had a poor prognosis, which was mainly due to its more-advanced stage compared to that of patients who received a DG. Early detection is important for improving the prognosis.

摘要

流行病学研究表明，全胃切除术（TGs）的实施数量持续增加。我们比较了接受全胃切除术患者与接受远端胃切除术（DG）患者的临床病理特征和预后。回顾性分析了696例行全胃切除术患者的病例。多因素分析显示，年龄、肿瘤大小、浆膜侵犯情况、淋巴结转移及可切除性是全胃切除术患者生存的重要预后因素。接受全胃切除术患者的5年生存率（39.5%）低于接受远端胃切除术患者（56.1%；P<0.001）。接受全胃切除术的患者预后较差，这主要是因为与接受远端胃切除术的患者相比，其分期更晚。早期发现对改善预后很重要。