Fenaux-Allard I, Bonneterre J, Vilain M O, Fenaux P, Cabaret V, Delobelle-Deroide A, Demaille A
Centre Oscar-Lambret, Lille.
J Gynecol Obstet Biol Reprod (Paris). 1991;20(2):163-7.
Between the 1st of January 1974 and the 30th of June 1989, we saw 9 cases of primary lymphoma of the breast at the Oscar Lambret Centre, all occurring in women. This comprised 0.27% of the malignant tumours of the breast and 3.2% of all non-Hodgkin lymphomas. 8 occurred on the right side and 1 on the left. There were multiple tumours in 5 cases. The clinical findings were always suggestive of a malignant condition and so were the mammography findings in 6 cases. Two patients had total mastectomy. In the other cases, the diagnosis was made (twice) by biopsy or by lumpectomy (5 cases). Using Kiel-Lennert's classification: 5 were highly malignant and 4 of low grade malignancy (using the Working Formulation, three were moderate and 4 were intermediate; 1 was very high grade and 1 intermediate or high). Treatment changed a lot during the period under consideration. Five patients are still alive without any recurrence. One died of lymphoma and two died of intercurrent causes and one died of unknown causes.
在1974年1月1日至1989年6月30日期间,我们在奥斯卡·兰布雷特中心共诊治了9例原发性乳腺淋巴瘤患者,均为女性。这占乳腺恶性肿瘤的0.27%,占所有非霍奇金淋巴瘤的3.2%。8例发生在右侧,1例发生在左侧。5例为多发肿瘤。临床检查结果均提示为恶性病变,6例乳腺X线检查结果也提示为恶性。2例行全乳切除术。其他病例中,诊断通过活检(2例)或肿块切除术(5例)做出。采用基尔-伦纳特分类法:5例为高度恶性,4例为低度恶性(按照工作分类法,3例为中度,4例为中间型;1例为极高分级,1例为中间型或高分级)。在所研究的这段时期内,治疗方法有很大变化。5例患者仍存活,无任何复发迹象。1例死于淋巴瘤,2例死于并发疾病,1例死因不明。