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[子宫动脉多普勒检查的价值以及高危妊娠中子宫和脐血流速度测定的相关性]

[Value of Doppler of the uterine arteries and the association of uterine and umbilical velocimetry in pregnancies at risk].

作者信息

Favre R, Ditesheim P J

机构信息

Département de Gynécologie-Obstétrique, CHU Vaudois, Lausanne.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1991;20(2):261-8.

PMID:2071872
Abstract

This study was designed to evaluate the role of Doppler velocimetry of uterine artery and of the association of uterine and umbilical artery. We use the index of Stuart S/D to characterize the uterine waveform. A value greater than or equal to 3 and/or the persistence of a notch is considered abnormal. When the uterine artery is pathological, we find more proteinuric hypertension, the incidence of intrauterine growth retardation (IURG) twice (p less than 0.001), the birthweight is significantly lower; the caesarean section rate for fetal distress is 35% for 11% in the other group (p less than 0.005), but the caesarean section rate for maternal indication is the same in the two groups. If we test the efficiency of the uterine Doppler study in prediction IUGR, we obtain a sensitivity of 42.5% and a positive predictive value of 74%. The population of high risk pregnancies is divided into four groups according to the Doppler findings. The first group contain normal values in the uteroplacental circulation and in the umbilical vessels, this association predict a normal outcome. The second group contain normal umbilical artery flow velocity waveform (FVW) and abnormal uteroplacental FVW, this pattern is associated with more severe hypertension and a rate of caesarean section of 16%. The final two groups contain patients with abnormal umbilical FVW and either normal or abnormal uteroplacental FVW. We find in these two groups the more complicated neonatal evolution, the incidence of caesarean section for fetal distress is more than 50%, the rate of IUGR is between 82% and 100%. The examination of the uteroplacental vessels permit the selection of patients with high risk of chronic fetal distress, therefore these pregnancies will have intensive surveillance with biophysical profile, umbilical and cerebral Doppler.

摘要

本研究旨在评估子宫动脉多普勒测速以及子宫动脉与脐动脉联合检测的作用。我们使用斯图尔特S/D指数来描述子宫波形特征。数值大于或等于3和/或切迹持续存在被视为异常。当子宫动脉出现病变时,我们发现蛋白尿性高血压更多见,胎儿宫内生长迟缓(IUGR)的发生率翻倍(p小于0.001),出生体重显著降低;因胎儿窘迫而行剖宫产的比例在该组为35%,而另一组为11%(p小于0.005),但两组因母体指征而行剖宫产的比例相同。如果我们测试子宫多普勒研究在预测IUGR方面的有效性,得到的敏感度为42.5%,阳性预测值为74%。根据多普勒检查结果,将高危妊娠人群分为四组。第一组子宫胎盘循环和脐血管值均正常,这种情况预示着正常结局。第二组脐动脉血流速度波形(FVW)正常,但子宫胎盘FVW异常,这种模式与更严重的高血压相关,剖宫产率为16%。最后两组包含脐FVW异常且子宫胎盘FVW正常或异常的患者。我们发现这两组新生儿病情发展更复杂,因胎儿窘迫而行剖宫产的发生率超过50%,IUGR发生率在82%至100%之间。对子宫胎盘血管的检查有助于筛选出慢性胎儿窘迫高危患者,因此这些妊娠将通过生物物理评分、脐动脉和脑动脉多普勒进行密切监测。

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