Frazer Ian H
The University of Queensland Diamantina Institute, Princess Alexandra Hospital, Woolloongabba, Qld 4102, Australia.
Sex Health. 2010 Sep;7(3):230-4. doi: 10.1071/SH09132.
Cervical cancer is initiated by infection of cervical epithelium with human papillomavirus. Vaccines have been developed, incorporating papillomavirus viral capsids and alum based adjuvants. In extensive clinical trials these vaccines have been shown safe and effective in preventing infection with, and disease caused by, the papillomavirus genotypes they incorporate, in women not already infected. These vaccines have the potential to reduce the global burden of cervical cancer by up to 70%.
宫颈癌是由人乳头瘤病毒感染宫颈上皮引发的。现已研发出包含乳头瘤病毒病毒衣壳和铝基佐剂的疫苗。在广泛的临床试验中，这些疫苗已被证明对于预防未感染的女性感染其所包含的乳头瘤病毒基因型以及由这些基因型引发的疾病是安全有效的。这些疫苗有潜力将全球宫颈癌负担降低多达70%。
