Takei Y, Mizuno K
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Mar 7;205(4):213-20. doi: 10.1007/BF00413449.
The lens, iris, and ciliary body from the eyes of patients with glaucoma with cataract were examined via electron microscopy, and the following results obtained. 1. Zonular bundles were encrusted with accumulations of pseudoexfoliative (PE) materials and fragmented zonular fibrils, especially on their lateral aspects. 2. PE materials ranged from 300 to 400 A in width, consisting of several subunits about 100 A wide. 3. Pigment epithelial cells of the iris and nonpigmented epithelial cells of the ciliary process occasionally contained many phagosomes engulfing pigment granules. 4. Near the ciliary process, degenerating zonular bundles were mostly replaced with PE materials and fragmented zonular fibrils, and a gradual transition was observed between them. From the above findings, it is probable that PE material might be mainly composed of degenerated zonular fibrils, which are presumed to be digested with lysosomal enzymes.
对患有青光眼合并白内障患者的眼睛中的晶状体、虹膜和睫状体进行了电子显微镜检查，并获得了以下结果。1. 小带束被假性剥脱（PE）物质积聚和破碎的小带纤维所覆盖，尤其是在其侧面。2. PE物质宽度在300至400埃之间，由几条约100埃宽的亚基组成。3. 虹膜色素上皮细胞和睫状体无色素上皮细胞偶尔含有许多吞噬色素颗粒的吞噬体。4. 在睫状体附近，退化的小带束大多被PE物质和破碎的小带纤维所取代，并且在它们之间观察到逐渐过渡。根据上述发现，PE物质可能主要由退化的小带纤维组成，推测这些纤维会被溶酶体酶消化。
