Faculty of Medicine, University of Oslo, Norway.
Neurology. 2010 Aug 24;75(8):712-7. doi: 10.1212/WNL.0b013e3181eee244. Epub 2010 Aug 18.
To examine the relationship between recurrent headache disorders (i.e., migraine and tension-type headache) and lifestyle factors (overweight, low physical activity, and smoking) in an unselected population study among adolescents.
In this cross-sectional study from Norway, a total of 5,847 students were interviewed about headache complaints and completed a comprehensive questionnaire including items concerning physical activity and smoking. In addition, they underwent a clinical examination with height and weight measurements. Adolescents with high physical activity who were not current smokers and not overweight were classified as having a good lifestyle status. These students were compared to those with 1 or more of the negative lifestyle factors present in regard to headache diagnosis and headache frequency.
In adjusted multivariate analyses, recurrent headache was associated with overweight (odds ratio [OR] = 1.4, 95% confidence interval [CI] 1.2-1.6, p < 0.0001), low physical activity (OR = 1.2, 95% CI 1.1-1.4, p = 0.002), and smoking (OR = 1.5, 95% CI 1.3-1.7, p < 0.0001). The prevalence of OR increased with more than 1 negative lifestyle factor present, evident for headache diagnoses and frequency.
The results from the present study show that overweight, smoking, or low physical activity are independently and in combination associated with recurrent headache among adolescents. The associations observed and the additive effect of these negative lifestyle factors on the prevalence of recurrent headache indicates possible targets for preventive measures.
在一项针对青少年的未选择人群研究中,研究复发性头痛疾病(即偏头痛和紧张性头痛)与生活方式因素(超重、低体力活动和吸烟)之间的关系。
在挪威进行的这项横断面研究中,共有 5847 名学生接受了头痛投诉访谈,并完成了一份综合问卷,其中包括有关体力活动和吸烟的项目。此外,他们还接受了身高和体重测量的临床检查。被归类为具有良好生活方式状态的青少年是指那些高体力活动、不吸烟且体重正常的人。将这些学生与存在 1 种或多种负面生活方式因素(即超重、低体力活动和吸烟)的学生进行头痛诊断和头痛频率比较。
在调整后的多变量分析中,复发性头痛与超重(比值比 [OR] = 1.4,95%置信区间 [CI] 1.2-1.6,p < 0.0001)、低体力活动(OR = 1.2,95% CI 1.1-1.4,p = 0.002)和吸烟(OR = 1.5,95% CI 1.3-1.7,p < 0.0001)有关。存在多个负面生活方式因素时,OR 的患病率会增加,这在头痛诊断和频率方面均可见。
本研究结果表明,超重、吸烟或低体力活动与青少年复发性头痛独立且组合相关。观察到的关联以及这些负面生活方式因素对复发性头痛患病率的累加效应表明,可能存在预防措施的目标。