School of Nursing, San Francisco State University, USA.
J Adv Nurs. 2010 Oct;66(10):2202-12. doi: 10.1111/j.1365-2648.2010.05399.x. Epub 2010 Aug 16.
This paper is a report of a study of the extent to which demographic characteristics, medication-related factors, hypertension-related knowledge and medication adherence predict systolic and diastolic blood pressure.
Little is known about predictors of hypertension control in Chinese elders.
A longitudinal study with a 3-month follow-up was conducted with 90 Chinese immigrants to the United States of America aged ≥65 years and recruited from 2006 to 2007. The independent variables were measured at baseline. Blood pressure was measured at 3 months. Multiple linear regression analysis was used to evaluate the independent effects of seven variables on change in blood pressure at 3 months.
Participants ranged in age from 66 to 92 years (Mean 76.7, sd 6.6). The overall regression model for systolic blood pressure was statistically significant (R² = 0.32, F = 4.37, P < 0.01). A higher number of prescribed oral medications (sr² = 0.06, t = 2.42, P = 0.02) and lower medication adherence (sr² = 0.07, t = -2.60, P = 0.01) were statistically significant determinants of an increased systolic blood pressure. The overall regression model for diastolic blood pressure was statistically significant (R² = 0.21, F = 2.39, P = 0.03). Male gender (sr² = 0.06, t = 2.26, P = 0.03) and lower medication adherence (sr² = 0.11, t = -3.03, P < 0.01) were statistically significant determinants of an increased diastolic blood pressure.
A greater number of prescribed medications and lower adherence predicted higher level of systolic blood pressure. Male gender and lower adherence were significantly associated with higher level of diastolic blood pressure. These predictors should be considered when designing interventions to help Chinese elders achieve better hypertension management.
本文报道了一项研究,旨在探讨人口统计学特征、药物相关因素、高血压相关知识和药物依从性对收缩压和舒张压的影响程度。
关于中国老年人高血压控制的预测因素知之甚少。
这是一项纵向研究,对 2006 年至 2007 年间招募的 90 名年龄≥65 岁的美国华裔移民进行了为期 3 个月的随访。在基线时测量了独立变量。在 3 个月时测量血压。采用多元线性回归分析评估了 7 个变量对 3 个月时血压变化的独立影响。
参与者年龄在 66 岁至 92 岁之间(平均 76.7,标准差 6.6)。收缩压的总体回归模型具有统计学意义(R²=0.32,F=4.37,P<0.01)。服用的口服药物种类较多(sr²=0.06,t=2.42,P=0.02)和药物依从性较低(sr²=0.07,t=-2.60,P=0.01)是收缩压升高的统计学显著决定因素。舒张压的总体回归模型具有统计学意义(R²=0.21,F=2.39,P=0.03)。男性(sr²=0.06,t=2.26,P=0.03)和较低的药物依从性(sr²=0.11,t=-3.03,P<0.01)是舒张压升高的统计学显著决定因素。
服用的药物种类较多和药物依从性较低预测收缩压水平较高。男性和较低的药物依从性与舒张压水平较高显著相关。在设计帮助中国老年人更好地控制高血压的干预措施时,应考虑这些预测因素。