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一名唐氏综合征患者的丙戊酸二钠应答性快速循环双相情感障碍：对唐氏综合征-躁狂假说的启示

Divalproex-responsive rapid cycling bipolar disorder in a patient with Down's syndrome: implications for the Down's syndrome-mania hypothesis.

作者信息

Sovner R

机构信息

Developmental Disabilities/Neuropsychiatric Service, Harvard Community Health Plan, Medford, Massachusetts.

出版信息

J Ment Defic Res. 1991 Apr;35 ( Pt 2):171-3. doi: 10.1111/j.1365-2788.1991.tb01048.x.

DOI:10.1111/j.1365-2788.1991.tb01048.x
PMID:2072396
Abstract

A case of rapid cycling bipolar disorder in a person with Down's syndrome, responsive to divalproex sodium, a valproic acid derivative, is presented. This case and three other reported cases of mania in association with Down's syndrome suggest that this chromosomal disorder does not preclude the development of mania.

摘要

本文报告了一例唐氏综合征患者的快速循环型双相情感障碍病例，该患者对丙戊酸衍生物丙戊酸二钠有反应。该病例以及其他三例已报告的与唐氏综合征相关的躁狂症病例表明，这种染色体疾病并不排除躁狂症的发生。

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