Institute of Psychiatry, University of Oslo, Oslo, Norway.
Psychiatry Res. 2011 Feb 28;185(3):309-14. doi: 10.1016/j.psychres.2010.07.026. Epub 2010 Aug 17.
Both schizophrenia (SCZ) and bipolar disorder (BD) are associated with disturbances in emotion processing. Previous studies suggest that patients with SCZ assess unpleasant pictures as less arousing than healthy controls (HC), while patients with BD assess neutral pictures as more arousing than HC. No previous studies have investigated whether there is a difference in emotional response across all three groups. Our aim was to explore whether there was a difference in the evaluation of valence and in arousal between SCZ, BD and HC for aversive and neutral pictures. We showed 72 pictures (neutral, non-socially aversive and socially aversive) from the International Affective Picture System (IAPS) to 347 subjects. There was a clear interaction effect between the diagnostic group and increasing picture aversiveness for both valence and arousal. There were no significant differences in valence ratings between the different groups or in arousal ratings on any type of stimuli between BD patients and HC. However, SCZ patients reported significantly lower arousal for aversive stimuli, particularly with a social content, when compared to BD patients and HC. This was more pronounced in females. The presence of lifetime psychotic symptoms did not influence emotional responses.
精神分裂症 (SCZ) 和双相情感障碍 (BD) 都与情绪处理障碍有关。先前的研究表明，与健康对照组 (HC) 相比，精神分裂症患者认为不愉快的图片的刺激性较小，而双相情感障碍患者认为中性图片的刺激性较大。以前没有研究调查过这三个群体在情绪反应上是否存在差异。我们的目的是探讨在评估厌恶和中性图片时，精神分裂症、双相情感障碍和健康对照组之间在效价和唤醒方面是否存在差异。我们向 347 名受试者展示了来自国际情感图片系统 (IAPS) 的 72 张图片（中性、非社会性厌恶和社会性厌恶）。对于效价和唤醒，诊断组和图片厌恶程度的增加之间存在明显的交互作用。不同组之间的效价评分没有显著差异，BD 患者和 HC 之间对任何类型的刺激的唤醒评分也没有差异。然而，与 BD 患者和 HC 相比，精神分裂症患者报告说对厌恶刺激的唤醒明显较低，特别是具有社会内容的刺激。这种情况在女性中更为明显。是否存在终生精神病症状并不影响情绪反应。
