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[整形外科医生在儿童坏疽性臁疮治疗中的作用:临床实例]

[Role of the plastic surgeon in the management of ecthyma gangrenosum in children: clinical example].

作者信息

Gonnelli D, Degardin N, Guidicelli T, Londner J, Magalon G, Bardot J

机构信息

Service de chirurgie plastique, reconstructrice et esthétique, hôpital de la Conception, 147, boulevard Baille, 13385 Marseille cedex 05, France.

出版信息

Ann Chir Plast Esthet. 2012 Aug;57(4):405-8. doi: 10.1016/j.anplas.2010.07.008. Epub 2010 Aug 17.

Abstract

Ecthyma gangrenosum is a cutaneous infection, which result from a Pseudomonas aeruginosa septicemia, encountered in most of the case in immunocompromised people. Authors demonstrate the important role of the plastic surgeon in the diagnosis and therapeutic management of the disease in children. An eight-month-old infant has been hospitalized for acute leukaemia. She developed an extensive painful macule in the buttocks and perineal area in a septic context. A multidisciplinary management allowed to set up an adapted antibiotherapy, an early escharrotomy, a protection of the wound by digestive and urine derivation and a reconstruction with wound healing by second intention and split thickness skin graft, which lead to a good quality cure and wound healing at the end of 37 days of evolution. This case demonstrates the importance of the surgical management in the treatment of ecthyma gangrenosum. The wound healing associated with a split thickness skin graft seems to be the less invasive solution in a frail patient and the fastest to re-start the chemotherapy.

摘要

坏疽性脓皮病是一种皮肤感染,由铜绿假单胞菌败血症引起,多见于免疫功能低下者。作者证明了整形外科医生在儿童该疾病诊断和治疗管理中的重要作用。一名八个月大的婴儿因急性白血病住院。在败血症的情况下,她的臀部和会阴区域出现了广泛的疼痛性斑疹。多学科管理使得能够制定合适的抗生素治疗方案、早期焦痂切开术、通过消化道和尿液引流保护伤口,并通过二期愈合和中厚皮片移植进行重建,在病程37天后实现了良好的治愈和伤口愈合。该病例证明了手术管理在坏疽性脓皮病治疗中的重要性。对于体弱患者,中厚皮片移植相关的伤口愈合似乎是侵入性最小的解决方案,也是重新开始化疗最快的方法。

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