Surukrattanaskul Supawan, Pittayapongpat Rosana, Wangtiraumnuay Nutsuchar
Department of Ophthalmology, Queen Sirikit National Institute of Child Health, Bangkok, Thailand.
IDCases. 2023 Sep 7;34:e01894. doi: 10.1016/j.idcr.2023.e01894. eCollection 2023.
Ecthyma gangrenosum is a skin manifestation of fatal septicemia. We report a case of periocular ecthyma gangrenosum, which is an uncommonly infected area and rarely reported in infants. A 1-month-old female infant with periocular ecthyma gangrenosum presented with a high-grade fever and acute left medial canthus of the eyelid swelling and erythema. Hemoculture at 6 h confirmed infection. Intravenous and topical antibiotics were administered. Daily dressing of the wound and noninvasive bedside escharectomy were performed. Cosmetically acceptable scar was achieved without additional surgery. The patient was considered to have congenital neutropenia due to persistent neutropenia and severe skin and mucosal infections in her first year of life. Noninvasive debridement of the wound reduces the risk of exposure keratitis, lacrimal drainage pathway damage, and the need for further surgical reconstruction. The cause of compromised immunity in infants with ecthyma gangrenosum should be investigated, and intensive follow-up is recommended.
坏疽性脓皮病是致命性败血症的一种皮肤表现。我们报告一例眼周坏疽性脓皮病病例,该部位感染并不常见,在婴儿中鲜有报道。一名1个月大的患有眼周坏疽性脓皮病的女婴,出现高热,左眼内眦眼睑急性肿胀和红斑。6小时后的血培养确诊感染。给予静脉和局部抗生素治疗。每日进行伤口换药并实施无创床边焦痂切除术。无需额外手术即获得了美容效果可接受的瘢痕。由于该患者在出生后第一年持续存在中性粒细胞减少以及严重的皮肤和黏膜感染,故考虑患有先天性中性粒细胞减少症。伤口的无创清创可降低暴露性角膜炎、泪道损伤风险以及进一步手术重建的必要性。对于患有坏疽性脓皮病的婴儿,应调查其免疫功能受损的原因,并建议进行密切随访。