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生殖器官脱垂复发的风险因素。

Risk factors for recurrence of genital prolapse.

机构信息

Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy.

出版信息

Curr Opin Obstet Gynecol. 2010 Oct;22(5):420-4. doi: 10.1097/GCO.0b013e32833e4974.

Abstract

PURPOSE OF REVIEW

To review the available evidence regarding those risk factors potentially predicting a recurrence of pelvic organ prolapse (POP).

RECENT FINDINGS

POP is a very common condition in parous women, requiring very often a surgical treatment which may need to be repeated in up to 29% of cases. In the past few years, researchers have focused their attention on the evaluation of risk factors involved in either POP development or recurrence. Recent papers have reported the importance of genetic factors that could be responsible for an inherited weakness of the pelvic floor, predisposing to POP occurrence and/or recurrence. Moreover, a history of genital prolapse at the time of an elective hysterectomy, as well as an inappropriate reconstructive surgical procedure, can predict and be associated with POP development.

SUMMARY

POP recurrence can be associated with a combination of predisposing, inciting, and intervening factors. Based on actual knowledge, it is not possible to weight or score the importance of each single risk factor reported in literature for the development of POP recurrence. Larger series (collected with validated diagnostic and therapeutic tools) and longer follow-up are, therefore, needed to draw definitive conclusions on this issue.

摘要

目的综述

旨在回顾那些可能预测盆腔器官脱垂(POP)复发的风险因素的现有证据。

最近的发现

POP 是经产妇中非常常见的疾病,通常需要手术治疗,多达 29%的病例需要重复手术。在过去的几年中,研究人员将注意力集中在评估与 POP 发展或复发相关的风险因素上。最近的研究报告了遗传因素的重要性,这些因素可能导致盆底先天薄弱,易发生 POP 发生和/或复发。此外,选择性子宫切除术时的生殖器脱垂史以及不适当的重建手术也可以预测并与 POP 的发展相关。

总结

POP 复发可与易患、激发和干预因素相关。根据现有知识,不可能对文献中报道的每个单一风险因素对 POP 复发的发展的重要性进行加权或评分。因此,需要更大的系列(使用经过验证的诊断和治疗工具收集)和更长的随访时间,才能对此问题得出明确的结论。

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