Department of Orthopaedic Surgery, Osaka Minami Medical Center, Osaka, Japan.
Clin Orthop Relat Res. 2011 Mar;469(3):884-9. doi: 10.1007/s11999-010-1529-8. Epub 2010 Aug 20.
Many studies that analyzed bone mineral density (BMD) and skeletal factors of hip fractures were based on uncalibrated radiographs or dual-energy xray absorptiometry (DXA).
QUESTIONS/PURPOSES: Spatial accuracy in measuring BMD and morphologic features of the femur with DXA is limited. This study investigated differences in BMD and morphologic features of the femur between two types of hip fractures using quantitative computed tomography (QCT).
Forty patients with hip fractures with normal contralateral hips were selected for this study between 2003 and 2007 (trochanteric fracture, n=18; femoral neck fracture, n=22). Each patient underwent QCT of the bilateral femora using a calibration phantom. Using images of the intact contralateral femur, BMD measurements were made at the point of minimum femoral-neck cross-sectional area, middle of the intertrochanteric region, and center of the femoral head. QCT images also were used to measure morphologic features of the hip, including hip axis length, femoral neck axis length, neck-shaft angle, neck width, head offset, anteversion of the femoral neck, and cortical index at the femoral isthmus.
No significant differences were found in trabecular BMD between groups in those three regions. Patients with trochanteric fractures showed a smaller neck shaft angle and smaller cortical index at the femoral canal isthmus compared with patients with femoral neck fractures.
We conclude that severe osteoporosis with thinner cortical bone of the femoral diaphysis is seen more often in patients with trochanteric fracture than in patients with femoral neck fracture.
Level IV, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.
许多分析髋部骨折骨密度(BMD)和骨骼因素的研究都是基于未经校准的射线照片或双能 X 射线吸收法(DXA)。
问题/目的:DXA 在测量 BMD 和股骨形态特征方面的空间准确性有限。本研究使用定量计算机断层扫描(QCT)研究了两种类型的髋部骨折之间 BMD 和股骨形态特征的差异。
2003 年至 2007 年间,选择了 40 例髋部骨折伴对侧正常髋部的患者进行本研究(转子间骨折,n=18;股骨颈骨折,n=22)。每位患者均使用校准体模对双侧股骨进行 QCT 检查。使用完整对侧股骨的图像,在股骨颈最小横截面积、转子间区域中部和股骨头中心处进行 BMD 测量。QCT 图像还用于测量髋部的形态特征,包括髋轴长度、股骨颈轴长度、颈干角、颈宽、头偏移、股骨颈前倾角和股骨峡部皮质指数。
三组患者在三个部位的骨小梁 BMD 无显著差异。转子间骨折患者的颈干角和股骨干管峡部的皮质指数均小于股骨颈骨折患者。
我们的结论是,转子间骨折患者的股骨干皮质较薄,骨质疏松更严重。
IV 级,预后研究。欲了解完整的证据水平描述,请参见作者指南。