Protea Biosciences, 955 Hartman Run Road, Morgantown, West Virginia 26507, USA. miaosheng·
J Org Chem. 2010 Sep 17;75(18):6149-53. doi: 10.1021/jo100954q.
A general approach to the synthesis of a new series of unique sulfate anionic acid-labile surfactants (AALS) was developed. In this approach, the ketal was derived from methyl pyruvate, and the sulfate motif was introduced via sulfitylation of the alcohol, oxidation, and finally conversion of the sulfate diester to the desired sodium salt. The physicochemical properties in aqueous solution of this novel series of surfactants, such as CMCs, solubility, acid lability, and stability were studied.
本文发展了一种通用的方法来合成一系列新型的硫酸阴离子酸不稳定表面活性剂（AALS）。在此方法中，缩酮由丙酮酸甲酯衍生而来，硫酸基团则通过醇的亚磺化、氧化以及最后将硫酸二酯转化为所需的钠盐引入。研究了该系列表面活性剂在水溶液中的物理化学性质，如 CMC、溶解度、酸不稳定性和稳定性等。
