Ayhan A, Tuncer Z S
Department of Obstetrics and Gynecology, Hacettepe University, School of Medicine, Ankara, Turkey.
J Surg Oncol. 1991 Jul;47(3):175-7. doi: 10.1002/jso.2930470308.
This study includes 278 cases of stage I and II cervical cancer subjected to radical hysterectomy and lymphadenectomy. The clinical experience of 278 cases is reviewed. Of these cases, 215 were in stage I, and 63 were in stage II. Intraoperative complications occurred at a rate of 9.7% and involved injuries to the great vessels, lower urinary tract, nerves, and rectum. Operative mortality was found to be 0.3%. Postoperative complications were observed in 20.1% of patients. Fistulae were observed in 8 (2.8%) patients. The overall survival rate was 83.8%. The 5-year survival rates for stages IA, IB, IIA, and IIB were 100.0%, 87.9%, 71.0%, and 64.0%, respectively. Pelvic lymph node metastases varied from 0% for stage IA to 40.0% for stage IIB and paraaortic involvement varied from 0% for stage IA to 50.0% for stage IIB. Radical surgery seems to be the treatment of choice for patients with early invasive cervical cancer.
本研究纳入了278例行根治性子宫切除术和淋巴结清扫术的Ⅰ期和Ⅱ期宫颈癌患者。回顾了这278例患者的临床经验。其中，215例为Ⅰ期，63例为Ⅱ期。术中并发症发生率为9.7%，包括大血管、下尿路、神经和直肠损伤。手术死亡率为0.3%。20.1%的患者出现术后并发症。8例（2.8%）患者出现瘘管。总生存率为83.8%。ⅠA期、ⅠB期、ⅡA期和ⅡB期的5年生存率分别为100.0%、87.9%、71.0%和64.0%。盆腔淋巴结转移率从ⅠA期的0%到ⅡB期的40.0%不等，腹主动脉旁受累率从ⅠA期的0%到ⅡB期的50.0%不等。根治性手术似乎是早期浸润性宫颈癌患者的首选治疗方法。
