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婴幼儿获得性气管狭窄

Acquired tracheal stenosis in infants and children.

作者信息

Weber T R, Connors R H, Tracy T F

机构信息

Department of Surgery, St. Louis University School of Medicine, Mo.

出版信息

J Thorac Cardiovasc Surg. 1991 Jul;102(1):29-34; discussion 34-5.

PMID:2072726
Abstract

Acquired tracheal stenosis in childhood is frequently difficult to manage because of poor healing, infection, and scarring. In a 10-year period, 62 patients (4 weeks to 14 years of age) were treated for acquired tracheal stenosis. The causes of stenosis were endotracheal intubation (44 patients), caustic aspiration (6 patients), recurrent infection (5 patients), bronchoscopic perforation (4 patients), and gastric aspiration (3 patients). The subglottic or upper trachea was involved in 47 patients, mid portion in 8, and distal or carinal area in 7. Fifty children underwent tracheostomy as part of the therapy, and 12 were managed without tracheostomy. Therapy was individualized, frequently sequentially, utilizing rigid or balloon dilatation (20 patients), bronchoscopic electrocoagulation resection (44 patients), steroid injection (48 patients), T tube stent (8 patients), resection with anastomosis (12 patients), cricoid split (3 patients), and rib cartilage graft (12 patients). Most patients required several techniques and repeated procedures to eventually achieve decannulation. Seven patients (11%) died of unrelated causes. Forty-four of 55 surviving patients (80%) are without tracheostomy, although 14 have required continued endotracheal treatment after tracheostomy removal (dilatation, endotracheal resection). This series demonstrates that acquired tracheal stenosis in childhood is a common, difficult problem, but manageable with the use of a variety of techniques. Resection and grafting procedures should be reserved for cases in which less complex modalities fail.

摘要

儿童获得性气管狭窄由于愈合不良、感染和瘢痕形成,常常难以处理。在10年期间,62例(年龄4周至14岁)获得性气管狭窄患者接受了治疗。狭窄的原因包括气管插管(44例)、腐蚀性物质误吸(6例)、反复感染(5例)、支气管镜穿孔(4例)和胃内容物误吸(3例)。声门下或气管上段受累47例,中段8例,远端或隆突区7例。50例儿童接受了气管造口术作为治疗的一部分,12例未行气管造口术。治疗是个体化的,常常是序贯进行,采用硬质或球囊扩张(20例)、支气管镜电凝切除术(44例)、类固醇注射(48例)、T形管支架置入(8例)、切除吻合术(12例)、环状软骨劈开术(3例)和肋软骨移植术(12例)。大多数患者需要几种技术和重复操作才能最终实现拔管。7例患者(11%)死于无关原因。55例存活患者中有44例(80%)无需气管造口术,尽管14例在气管造口术拔除后仍需要持续的气管内治疗(扩张、气管内切除术)。本系列研究表明,儿童获得性气管狭窄是一个常见且棘手的问题,但采用多种技术可以处理。切除和移植手术应保留用于较简单方法失败的病例。

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