Department of Neurosurgery, Changhai Hospital, Second Military Medical University, 168 Changhai Road, Shanghai 200433, China.
J Clin Neurosci. 2010 Nov;17(11):1395-8. doi: 10.1016/j.jocn.2010.03.035. Epub 2010 Aug 19.
The aim of this study was to identify image-based morphological parameters that correlated with the formation of internal carotid artery-posterior communicating artery (ICA-PcomA) aneurysms. Morphological parameters obtained from 3-dimensional digital subtraction angiography (3D-DSA) were evaluated from nine patients with ICA-PcomA aneurysms, including the diameter of the ICA (Dica) and PcomA (Dpcom), the angle between the ICA and the origin of the PcomA (Apcom), and the angle between the ophthalmic and communicating segments of the ICA (Aica). Measurements were performed on both sides of each patient. Parameters were analyzed with a paired-samples t-test for significance. In additional, receiver operating characteristic (ROC) analysis was performed on the significant parameter. Statistically significant differences were found between the aneurysmal (45.28±29.07°) and control sides (79.22±17.83°) for Apcom (p=0.020). In the ROC analysis, the area under the curve value of Apcom was 0.852, and the threshold for optimal sensitivity and specificity was 52.25°. Therefore, the Apcom parameter was correlated with the formation of an ICA-PcomA aneurysm, and seems to be a promising morphological parameter for risk assessment of aneurysm formation.
本研究旨在确定与颈内动脉-后交通动脉（ICA-PcomA）动脉瘤形成相关的基于图像的形态学参数。对 9 例 ICA-PcomA 动脉瘤患者的三维数字减影血管造影（3D-DSA）获得的形态学参数进行了评估，包括颈内动脉（Dica）和后交通动脉（Dpcom）直径、颈内动脉与后交通动脉起点之间的夹角（Apcom）以及颈内动脉眼段与交通段之间的夹角（Aica）。对每位患者的两侧进行了测量。采用配对样本 t 检验对参数进行显著性分析。此外，对有显著性的参数进行了受试者工作特征（ROC）分析。Apcom 角在动脉瘤侧（45.28±29.07°）和对照组（79.22±17.83°）之间存在统计学显著差异（p=0.020）。在 ROC 分析中，Apcom 的曲线下面积值为 0.852，最佳灵敏度和特异性的阈值为 52.25°。因此，Apcom 参数与 ICA-PcomA 动脉瘤的形成相关，似乎是动脉瘤形成风险评估的有前途的形态学参数。
