Unidad de Biotecnología, Centro de Investigación Científica de Yucatán, Calle 43 No. 130, Col. Chuburná de Hidalgo, Mérida 97200, Yucatán, Mexico.
J Ethnopharmacol. 2010 Oct 28;132(1):303-8. doi: 10.1016/j.jep.2010.08.040. Epub 2010 Aug 20.
Since one of the main health problems of the indigenous population are infectious bowel diseases, we decided to test Mayan medicinal potions used to treat these conditions against some of the causal agents.
Thirty-one herbal formulations used for the treatment of infectious bowel diseases were prepared according to the collected ethnobotanical data. Their activities were tested against some of the causal agents of diarrheic symptoms, such as Entamoeba histolytica, Giardia lamblia, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi and Shigella flexneri.
Nine formulations were active against bacteria (MIC=0.5 mg/ml), four on Entamoeba histolytica, and seven on Giardia lamblia (IC(50)≤20 μg/ml).
This work supports the use of the traditional Mayan formulations against some infectious bowel diseases, and it is the first step towards their study.
由于土著居民的主要健康问题之一是传染性肠道疾病，我们决定针对这些疾病的一些病原体来测试用于治疗这些疾病的玛雅药用制剂。
根据收集到的民族植物学数据，制备了 31 种用于治疗传染性肠道疾病的草药配方。针对一些引起腹泻症状的病原体，如溶组织内阿米巴、蓝氏贾第鞭毛虫、大肠杆菌、肺炎克雷伯菌、伤寒沙门氏菌和福氏志贺菌，对这些配方的活性进行了测试。
有 9 种配方对细菌（MIC=0.5mg/ml）具有活性，4 种对溶组织内阿米巴具有活性，7 种对蓝氏贾第鞭毛虫具有活性（IC（50）≤20μg/ml）。
这项工作支持传统的玛雅配方用于治疗一些传染性肠道疾病，这是对它们进行研究的第一步。
