Vanderzwalmen P, Fallet C
IVF Centers Prof. Zech, Bregenz, Autriche.
J Gynecol Obstet Biol Reprod (Paris). 2010 Apr;39(1 Suppl):22-5. doi: 10.1016/S0368-2315(10)70008-9.
The presence of nuclear vacuoles in human sperm decreases pregnancy rates. Intracytoplasmic morphologically selected sperm injection (ISMI) increases pregnancy rate rather than ICSI after real time fine morphology of motile human sperm (MSOME). However, the exact indications of IMSI are on debate.
人类精子中核空泡的存在会降低妊娠率。在对活动的人类精子进行实时精细形态学观察（MSOME）后，胞浆内形态学选择精子注射（IMSI）比卵胞浆内单精子注射（ICSI）更能提高妊娠率。然而，IMSI的确切适应证仍存在争议。
