Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry and Life Science, Zhejiang Normal University, 321004 Jinhua, PR of China.
Org Biomol Chem. 2010 Oct 21;8(20):4527-9. doi: 10.1039/c0ob00272k. Epub 2010 Aug 23.
The diversely functionalized tricyclic tetrazoles were synthesised from readily available substrates via intramolecular 1,3-dipolar cycloaddition as the key step in good yields (53-78% yield for two steps) with high enantioselectivities (81-99% ee).
通过分子内 1,3-偶极环加成反应，从易得的底物出发，合成了具有多样功能化的三环四唑，以高产率（两步总产率为 53-78%）和高对映选择性（81-99%ee）为关键步骤。
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