Depression after myocardial infarction.

Depression is an important disease state that requires significant time and resources to manage properly. The presence of depression in patients with cardiovascular disease has been strongly associated with detrimental effects in terms of morbidity and mortality. Although several large-scale and small studies have evaluated various interventions in the management of depression after myocardial infarction, a significant portion of these data have provided more questions than answers. Although limited, the randomized prospective clinical trial data evaluating interventions for the management of depression after myocardial infarction in patients with ischemic heart disease continue to produce promising findings for progressive and improved management of these devastating diseases.