Nowicki M, Rychlik A, Nieradka R, Kander M, Depta A, Chrzastowska M
Department of Clinical Diagnostics, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 14, 10-719 Olsztyn.
Pol J Vet Sci. 2010;13(2):363-71.
Renal biopsies were carried out in 25 mixed-breed dogs of both sexes, aged 6 to 11 years, using an automatic, laparoscopy-guided method. The aim of the study was to apply and evaluate the usefulness of this technique in the diagnosis of renal pathologies in dogs. Twenty biopsy specimens were obtained from the right kidney and five--from the left kidney. As many as 24 of the 25 effectively collected biopsy specimens were classified as excellent (96%). Significant histopathological changes were found in 23 of the 25 biopsies performed. The results of histopathological analyses show a predominance of glomerular lesions over interstitial lesions, mostly mesangial glomerulonephritis, membranous and membrane-proliferative glomerulonephritis. The study confirmed that laparoscopy-guided biopsy of the kidney in dogs is a safe and a highly useful diagnostic technique. The results of histopathological analyses of biopsy specimens correlated with clinical history, clinical examination results, blood and urine tests and ultrasound examination results have a great diagnostic value and they significantly affect treatment and prognosis. Laparoscopy-guided biopsy supports the diagnosis and differentiation of glomerular and interstitial lesions and renal neoplasia in dogs.
对25只年龄在6至11岁的不同性别的杂种犬进行了肾活检,采用自动腹腔镜引导方法。本研究的目的是应用并评估该技术在犬肾病理学诊断中的实用性。从右肾获取了20个活检标本,从左肾获取了5个。25个有效采集的活检标本中多达24个被归类为优秀(96%)。在25例进行活检的病例中,有23例发现了明显的组织病理学变化。组织病理学分析结果显示,肾小球病变比间质病变更为常见,主要是系膜增生性肾小球肾炎、膜性和膜增生性肾小球肾炎。该研究证实,腹腔镜引导下犬肾活检是一种安全且非常有用的诊断技术。活检标本的组织病理学分析结果与临床病史、临床检查结果、血液和尿液检查以及超声检查结果相关,具有很大的诊断价值,并且对治疗和预后有显著影响。腹腔镜引导下活检有助于犬肾小球和间质病变以及肾肿瘤的诊断和鉴别。