University of Cincinnati Department of Surgery, Division of Trauma/Critical Care, Cincinnati, OH 45267-0558, USA.
Resuscitation. 2010 Sep;81(9):1148-51. doi: 10.1016/j.resuscitation.2010.05.006. Epub 2010 Jun 17.
In a contaminated environment, respiratory protection for ventilator dependent patients can be achieved by attaching a chemical, biological, radiological, or nuclear (CBRN) filter to the air intake port of a portable ventilator. We evaluated the effect of the filter on battery performance of four portable ventilators in a laboratory setting.
Each ventilator was attached to a test lung. Ventilator settings were: assist control (AC) mode, respiratory rate 35 bpm, tidal volume 450 ml, positive end-expiratory pressure (PEEP) 10 cm H(2)O, inspiratory time 0.8 s, and FIO(2) 0.21. Ventilators were operated until the battery was fully discharged. We also evaluated the ventilators' ability to deliver all the gas through the CBRN filter and analyzed the pressures required to breathe through the anti-asphyxiation valve of a failed device.
The range of battery life varied widely across different ventilator models (99.8-562.6 min). There was no significant difference in battery life (p<0.01) when operating with or without the CBRN filter attached. Only the Impact 731 routed all inspired gases through the CBRN filter. The pressure required to breathe though the failed device was -4 cm H(2)O to -9 cm H(2)O.
Duration of operation from the internal battery was not altered by attachment of the CBRN filter. The use of a CBRN filter is necessary for protection of ventilator dependent patients when environmental contamination is present, although conditions exist where all gas does not pass through the filter with some ventilators under normal operating conditions.
在污染环境中，可以通过将化学、生物、放射性或核（CBRN）过滤器连接到便携式呼吸机的进气口来为依赖呼吸机的患者提供呼吸保护。我们在实验室环境中评估了该过滤器对四种便携式呼吸机电池性能的影响。
将每个呼吸机连接到测试肺。呼吸机设置为：辅助控制（AC）模式，呼吸频率 35 次/分，潮气量 450 毫升，呼气末正压（PEEP）10 厘米 H₂O，吸气时间 0.8 秒，吸入氧浓度（FIO₂）0.21。呼吸机一直运行直到电池完全放电。我们还评估了呼吸机通过 CBRN 过滤器输送所有气体的能力，并分析了通过故障设备的窒息防护阀呼吸所需的压力。
不同呼吸机型号的电池寿命范围差异很大（99.8-562.6 分钟）。在连接或不连接 CBRN 过滤器的情况下，电池寿命没有显著差异（p<0.01）。只有 Impact 731 将所有吸入气体都通过 CBRN 过滤器输送。通过故障设备呼吸所需的压力为-4 厘米 H₂O 至-9 厘米 H₂O。
在存在环境污染的情况下，为依赖呼吸机的患者提供保护时，需要使用 CBRN 过滤器，但是在某些情况下，并非所有呼吸机在正常运行条件下都能使所有气体通过过滤器。连接 CBRN 过滤器不会改变内部电池的运行时间。
