Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia.
Health Policy. 2011 Feb;99(2):139-48. doi: 10.1016/j.healthpol.2010.08.002. Epub 2010 Aug 21.
This study evaluated Australian community pharmacists' rate of generic medicine substitution, patient acceptance of generic substitution and cost-savings achieved for patients from substitution.
A national stratified sample of 500 Australian pharmacies was randomly selected from different geographical areas. The data of the first 25 original PBS prescription items dispensed on one working day eligible for generic substitution were collected from each pharmacy.
Responses were received from 82 pharmacies with a response rate of 16.4%. The pharmacists recommended generics for 96.4% (1461/1515) of the prescription items which were eligible for substitution. The generic substitution recommendation rate in urban (98.7%) and rural areas (98.0%) was significantly higher than remote areas (91.6%). Conversely, patients' acceptance in remote areas (84.5%) was significantly higher than rural (78.6%) and urban areas (73.2%). Patients with chronic diseases demonstrated significantly lower acceptability (72.4%) than patients with acute conditions (81.6%). Through acceptance of substitution, the patients' medicines expenditure reduced by around 21%.
Australian community pharmacists demonstrated a high rate of recommending generic substitution. However, to optimize the generic medicines utilization, patients' acceptance requires further improvement.
本研究评估了澳大利亚社区药剂师进行仿制药替代的比率、患者对替代的接受程度以及为患者节省的成本。
从不同地理区域随机抽取了 500 家澳大利亚药店作为全国分层样本。从每家药店收集一个工作日内符合仿制药替代条件的前 25 个原始 PBS 处方项目的第一个处方数据。
收到了 82 家药店的回复，回复率为 16.4%。药剂师建议对 1515 个符合替代条件的处方项目中的 96.4%（1461 个）使用仿制药。城市（98.7%）和农村地区（98.0%）的仿制药替代推荐率明显高于偏远地区（91.6%）。相反，偏远地区（84.5%）的患者接受率明显高于农村地区（78.6%）和城市地区（73.2%）。慢性病患者的接受率（72.4%）明显低于急性病患者（81.6%）。通过接受替代，患者的药品支出减少了约 21%。
澳大利亚社区药剂师推荐仿制药替代的比例很高。然而，要优化仿制药的利用，还需要进一步提高患者的接受程度。
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