Department of Neurosurgery, Xuan Wu Hospital, Capital Medical University, Beijing, China.
Acta Neurochir (Wien). 2010 Dec;152(12):2191-5. doi: 10.1007/s00701-010-0778-3. Epub 2010 Aug 24.
Cervicocephalic fibromuscular dysplasia (FMD) is an idiopathic, non-inflammatory and non-atherosclerotic arteriopathy which usually affects small- and medium-sized cervical arteries distributed at the atlas and axis interspace. Few cervicocephalic FMD patients are associated with multiple intracranial aneurysms which may rupture or develop. So the authors describe a cervicocephalic FMD patient with a history of right oculomotor palsy in 2000. Angiography revealed bilateral internal carotid artery (ICA) aneurysms and a fusiform aneurysm in right vertebral artery. Typical "string-of-beads" phenomenon was observed in V2 segment of left vertebral artery. The right ICA giant aneurysm was treated by right ICA occlusion and superficial temporal artery (STA)-middle cerebral artery (MCA) bypass at that time. Five years later, the patient presented with paroxysmal weakness in right limbs. The subsequent angiography showed the enlargement of left ICA aneurysm. It was treated satisfactorily with left external carotid artery-saphenous vein-MCA bypass and left ICA ligation. During the long-term follow-up, the patient kept no neurological deficit and the angiography showed good patency of bilateral grafts and the lesions in bilateral vertebral arteries remained unchanged.
头颈部纤维肌发育不良(FMD)是一种特发性、非炎症性、非动脉粥样硬化性的血管疾病,通常影响分布于寰枢椎间隙的颈段中小动脉。少数头颈部 FMD 患者伴有多发颅内动脉瘤,这些动脉瘤可能会破裂或进展。因此,作者描述了一位头颈部 FMD 患者,该患者曾于 2000 年出现右侧动眼神经麻痹。血管造影显示双侧颈内动脉(ICA)动脉瘤和右侧椎动脉梭形动脉瘤。左侧椎动脉 V2 段可见典型的“串珠样”现象。当时,右侧巨大 ICA 动脉瘤通过右侧 ICA 闭塞和颞浅动脉(STA)-大脑中动脉(MCA)旁路治疗。5 年后,患者出现右侧肢体阵发性无力。随后的血管造影显示左侧 ICA 动脉瘤增大。通过左侧颈外动脉-大隐静脉-MCA 旁路和左侧 ICA 结扎治疗,效果满意。在长期随访中,患者无神经功能缺损,血管造影显示双侧移植血管通畅良好,双侧椎动脉病变无变化。