Murcia J, Vázquez J, Hierro L, de la Vega A, Santamaría M L, Gámez M, Camarena C, Díaz M C, Turrión V, de Vicente E
Unidad Interhospitalaria de Trasplante Hepático, Hospital Infantil La Paz, Madrid.
Cir Pediatr. 1990 Jul;3(3):121-4.
Currently, the incidence of one episode of infection after liver transplantation is 83 for 100 and 50 for 100 of them are severe. We have studied 30 patients who underwent liver transplantation, ten of them received a second graft. All patients were treated prophylactic with antibiotics 48 hours and selective bowel decontamination, in 23 we used ganciclovir prophylactic. The incidence of infection was 73 for 100, 40 episodes of bacterial infection, eight fungal and ten viral. The direct relationship of infection and mortality was seen in six patients. We studied different risk factors of infection and we found a correlation between surgical time, prior operations and arterial thrombosis with infections.
目前,肝移植后发生一次感染的发生率为每100例中有83例,其中50例为严重感染。我们研究了30例接受肝移植的患者,其中10例接受了二次移植。所有患者均在48小时内接受抗生素预防性治疗和选择性肠道去污,23例患者使用更昔洛韦进行预防性治疗。感染发生率为每100例中有73例,其中40例为细菌感染,8例为真菌感染,10例为病毒感染。6例患者出现感染与死亡率之间的直接关系。我们研究了不同的感染危险因素,发现手术时间、既往手术和动脉血栓形成与感染之间存在相关性。