强碱性溶剂促进亲核 CH 活化。

Acceleration of nucleophilic CH activation by strongly basic solvents.

机构信息

The Scripps Energy Laboratories, The Scripps Research Institute, Scripps Florida, Jupiter, Florida 33458, USA.

出版信息

J Am Chem Soc. 2010 Sep 15;132(36):12542-5. doi: 10.1021/ja102518m.

PMID:20734988

Abstract

(IPI)Ru(II)(OH)(n)(H(2)O)(m), 2, where IPI is the NNN-pincer ligand, 2,6-diimidizoylpyridine, is shown to catalyze H/D exchange between hydrocarbons and strongly basic solvents at higher rates than in the case of the solvent alone. Significantly, catalysis by 2 is accelerated rather than inhibited by increasing solvent basicity. The evidence is consistent with the reaction proceeding by base modulated nucleophilic CH activation.

摘要

(IPI)Ru(II)(OH)(n)(H(2)O)(m)，2，其中 IPI 是 NNN-三齿配体 2,6-二咪唑吡啶，被证明可催化烃与强碱性溶剂之间的 H/D 交换，其反应速率高于仅使用溶剂的情况。重要的是，增加溶剂碱性反而会加速而不是抑制 2 的催化作用。这一证据与通过碱调节的亲核 CH 活化进行反应的观点一致。