快速流感抗原检测对新型甲型H1N1流感的诊断价值
Diagnostic value of the rapid influenza antigen test for novel influenza A (H1N1).
作者信息
Lee Hyang-Mee, Park Hoon-Ki, Hwang Hwan-Sik, Chun Min-Young, Pai Hyun-Joo, Oh Sung Hee, Kim Duck-An
机构信息
Department of Family Medicine, College of Medicine, Hanyang University, Seoul, South Korea.
出版信息
Scand J Infect Dis. 2011 Jan;43(1):43-6. doi: 10.3109/00365548.2010.508463. Epub 2010 Aug 25.
We administered both the rapid antigen test and real-time reverse transcriptase polymerase chain reaction (RT-PCR) test to 2154 patients in order to assess the diagnostic value of the rapid antigen test during Korean pandemics of H1N1 2009. The overall sensitivity was 70.0%, specificity was 97.5%, positive predictive value was 97.4%, and negative predictive value was 71.2%. The sensitivity fell and the negative predictive value decreased as the RT-PCR positive rate increased.
为评估快速抗原检测在2009年韩国甲型H1N1流感大流行期间的诊断价值，我们对2154例患者同时进行了快速抗原检测和实时逆转录聚合酶链反应（RT-PCR）检测。总体敏感性为70.0%，特异性为97.5%，阳性预测值为97.4%，阴性预测值为71.2%。随着RT-PCR阳性率的增加，敏感性下降，阴性预测值降低。
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