足月和早产儿尿液中3',5'-单磷酸腺苷（cAMP）和肌酐的含量。

Urinary content of 3',5'-adenosine monophosphate (cAMP) and creatinine in full-term and premature infants.

作者信息

Maxwell G M, Dahlenburg G W, Rencis V

出版信息

Biol Neonate. 1978;33(1-2):55-61. doi: 10.1159/000241051.

PMID:207364

Abstract

Cyclic 3',5'-monophosphate (c-AMP) and creatinine were measured in full-term and premature infants. In normals, values for c-AMP were highest on days 1 and 2 (1.3-1.5 nmol/ml) and decreased thereafter. In prematures the c-AMP values were significantly lower than in the full-term infants. There was a rough correlation with birth weight. Creatinine values were closely reflected by the c-AMP levels. Changes found in neonatal jaundice, hypocalcaemia, respiratory distress syndrome, and anoxia could be attributed to prematurity. No diurnal variation in c-AMP values was found.

摘要

对足月和早产婴儿的环磷腺苷（c-AMP）和肌酐进行了测量。在正常婴儿中，c-AMP值在出生后第1天和第2天最高（1.3 - 1.5纳摩尔/毫升），此后下降。早产儿的c-AMP值明显低于足月婴儿。其与出生体重大致相关。肌酐值与c-AMP水平密切相关。新生儿黄疸、低钙血症、呼吸窘迫综合征和缺氧中发现的变化可能归因于早产。未发现c-AMP值有昼夜变化。