Department of Anesthesiology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Anesth Analg. 2010 Nov;111(5):1133-7. doi: 10.1213/ANE.0b013e3181f2ecc7. Epub 2010 Aug 24.
Postoperative respiratory complications related to endotracheal intubation usually present as cough, sore throat, hoarseness, and blood-streaked expectorant. In this study, we investigated the short-term (hours) impact of measuring and controlling endotracheal tube cuff (ETTc) pressure on postprocedural complications.
Five hundred nine patients from 4 tertiary care university hospitals in Shanghai, China scheduled for elective surgery under general anesthesia were assigned to a control group without measuring ETTc pressure, and a study group with ETTc pressure measured and adjusted. The duration of the procedure and duration of endotracheal intubation were recorded. Twenty patients whose duration of endotracheal intubation was between 120 and 180 minutes were selected from each group and examined by fiberoptic bronchoscopy immediately after removing the endotracheal tube. Endotracheal intubation-related complications including cough, sore throat, hoarseness, and blood-streaked expectorant were recorded at 24 hours postextubation.
There was no significant difference in sex, age, height, weight, procedure duration, and duration of endotracheal intubation between the 2 groups. The mean ETTc pressure measured after estimation by palpation of the pilot balloon of the study group was 43 ± 23.3 mm Hg before adjustment (the highest was 210 mm Hg), and 20 ± 3.1 mm Hg after adjustment (P < 0.001). The incidence of postprocedural sore throat, hoarseness, and blood-streaked expectoration in the control group was significantly higher than in the study group. As the duration of endotracheal intubation increased, the incidence of sore throat and blood-streaked expectoration in the control group increased. The incidence of sore throat in the study group also increased with increasing duration of endotracheal intubation. Fiberoptic bronchoscopy in the 20 patients showed that the tracheal mucosa was injured in varying degrees in both groups, but the injury was more severe in the control group than in the study group.
ETTc pressure estimated by palpation with personal experience is often much higher than measured or what may be optimal. Proper control of ETTc pressure by a manometer helped reduce ETT-related postprocedural respiratory complications such as cough, sore throat, hoarseness, and blood-streaked expectoration even in procedures of short duration (1-3 hours).
与气管插管相关的术后呼吸系统并发症通常表现为咳嗽、咽痛、声音嘶哑和带血丝的痰。在这项研究中,我们研究了测量和控制气管插管套囊(ETTc)压力对术后并发症的短期(数小时)影响。
来自中国上海 4 家三级护理大学医院的 509 名择期全身麻醉手术患者被分为对照组,不测量 ETTc 压力,以及研究组,测量和调整 ETTc 压力。记录手术过程的持续时间和气管插管的持续时间。从每组中选择 20 名气管插管时间在 120-180 分钟之间的患者,在拔除气管插管后立即进行纤维支气管镜检查。在拔除气管插管后 24 小时记录与气管插管相关的并发症,包括咳嗽、咽痛、声音嘶哑和带血丝的痰。
两组患者在性别、年龄、身高、体重、手术时间和气管插管时间方面无显著差异。研究组通过触摸测压表测量后测量的 ETTc 压力平均为 43±23.3mmHg(最高为 210mmHg),调整后为 20±3.1mmHg(P<0.001)。对照组术后咽痛、声音嘶哑和带血丝痰的发生率明显高于研究组。随着气管插管时间的延长,对照组咽痛和带血丝痰的发生率增加。随着气管插管时间的延长,研究组咽痛的发生率也增加。两组 20 名患者的纤维支气管镜检查显示,两组的气管黏膜均有不同程度的损伤,但对照组的损伤比研究组更严重。
用个人经验触诊估计的 ETTc 压力往往远高于测量或可能的最佳压力。通过压力计适当控制 ETTc 压力有助于减少与 ETT 相关的术后呼吸系统并发症,如咳嗽、咽痛、声音嘶哑和带血丝的痰,即使在短时间(1-3 小时)的手术中也是如此。