Technische Universität Darmstadt, Fachgebiet Materialanalytik, Petersenstr. 23, D-64287 Darmstadt, Germany.
Chem Commun (Camb). 2010 Sep 28;46(36):6690-2. doi: 10.1039/c0cc01632b. Epub 2010 Aug 25.
Here, we demonstrate an anion controlled molecular gate based on synthetic ion channels modified with polyethyleneimine. For single conical nanochannels, addition of ATP leads to significant decrease in the rectified ion flux, representing the closure of the ionic gate. Complementary experiments performed with nanoporous membranes show that the flux of charged dye (NDS(2-)) through a cylindrical nanochannel array diminishes by the co-addition of ATP in the analyte solution.
在这里，我们展示了一种基于聚亚乙基亚胺修饰的合成离子通道的阴离子控制分子门。对于单个锥形纳米通道，添加 ATP 会导致整流离子通量显著降低，表明离子门关闭。在纳米多孔膜上进行的补充实验表明，当分析物溶液中共同添加 ATP 时，带电荷染料（NDS(2-)) 通过圆柱形纳米通道阵列的通量会减小。
