Bentouati L, Baboli M S, Hachem H, Hamza M, Canal P, Soula G
Département de Biologie Clinique, Centre Claudius Regaud, Toulouse, France.
Clin Chim Acta. 1990 Dec 13;193(1-2):93-102. doi: 10.1016/0009-8981(90)90013-i.
An unexplained hyperphosphatasemia was noted in a healthy 47-year-old woman. The electrophoretic pattern on agarose gel with and without wheat germ lectin of the serum of this patient showed the presence of three isoforms which have been characterised as being of intestinal origin: their biochemical (neuraminidase, phenylalanine) and thermodenaturation properties are similar to those of intestinal tissue extract. The pI and pH optima of these isoforms agree with an intestinal origin. Our results suggest the existence of different allelozymes of intestinal alkaline phosphatase.
在一名47岁健康女性中发现了不明原因的高磷酸酶血症。该患者血清在有无麦胚凝集素的琼脂糖凝胶上的电泳图谱显示存在三种同工型，其已被鉴定为肠道来源：它们的生化特性（神经氨酸酶、苯丙氨酸）和热变性特性与肠道组织提取物相似。这些同工型的等电点和最适pH值与肠道来源相符。我们的结果表明存在肠道碱性磷酸酶的不同等位酶。
