化疗相关的视觉系统毒性。
Chemotherapy-related visual system toxicity.
机构信息
Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, USA.
出版信息
Adv Exp Med Biol. 2010;678:113-8. doi: 10.1007/978-1-4419-6306-2_14.
Most, if not all, of the studies that report cognitive impairments in patients who have been treated with cancer chemotherapy also report deficits involving the visual system (e.g., visual-spatial function or visual memory). The visual system seems like a likely susceptible target of cytotoxic drugs. Therefore, some portion of the vision-related cognitive deficits ofchemo fog/chemo brain might result from a direct action of the drugs or from site/site interaction between effects on the visual system and other critical brain regions. This chapter is a succint summary of a more expanded review.
大多数（如果不是全部的话）报道癌症化疗患者认知障碍的研究也报告了涉及视觉系统的缺陷（例如，视觉空间功能或视觉记忆）。视觉系统似乎是细胞毒性药物的一个易感目标。因此，化疗后认知障碍/化疗脑的某些与视觉相关的认知缺陷可能是由于药物的直接作用，或者是由于药物对视觉系统和其他关键大脑区域的影响在部位/部位之间的相互作用所致。本章是对更广泛的综述的简要总结。
Zotero 插件