Department of Orthodontics, Cleft Palate Team and Craniofacial Team, Erasmus MC-Sophia, University Medical Center, Room Sp 1408, Dr Molewaterplein 60, 3015 GJ Rotterdam, the Netherlands.
J Dent Res. 2010 Dec;89(12):1368-72. doi: 10.1177/0022034510378425. Epub 2010 Aug 25.
Hemifacial microsomia (HFM) is a congenital disorder marked by facial asymmetry. Whether facial asymmetry accounts for asymmetrical dental development is unknown. There are few data on dental development relative to mandibular development or severity of HFM, or on development over time. We hypothesized that when mandibular development was severely disturbed, local dental development was also affected. We compared dental development scores between affected and non-affected mandibular sides in patients with HFM (n = 84) and compared these data with those collected from Dutch control children (n = 451). Logistic functions were constructed for dental age over time for all four Pruzansky/Kaban types. The results showed a tendency toward delayed dental development in Pruzansky/Kaban types IIb and III at younger ages. The temporary delay of tooth formation in patients with severe forms of HFM and the distribution of agenic teeth suggest an interaction between mandibular and dental development.
半面短小症（HFM）是一种以面部不对称为特征的先天性疾病。面部不对称是否导致牙齿发育不对称尚不清楚。关于下颌骨发育与 HFM 的严重程度或随时间的发展相对的牙齿发育的数据很少。我们假设当下颌骨发育严重受干扰时，局部牙齿发育也会受到影响。我们比较了 HFM 患者（n = 84）受影响和不受影响的下颌侧的牙齿发育评分，并将这些数据与从荷兰对照儿童（n = 451）收集的数据进行了比较。为所有四种 Pruzansky/Kaban 类型构建了随时间推移的牙齿年龄的逻辑函数。结果表明，在年龄较小的情况下，Pruzansky/Kaban 类型 IIb 和 III 的牙齿发育有延迟的趋势。严重 HFM 患者中牙齿形成的暂时延迟和无牙的分布表明下颌骨和牙齿发育之间存在相互作用。
