Gorodetskiĭ V P, Zhuchenko A A, Korol' A B
Genetika. 1990 Nov;26(11):1942-52.
A number of theoretical models have been developed in population genetics to explain the evolution of recombination system under natural selection for adaptive traits. Using Drosophila cage populations of large size the effect of selection for resistance to daily temperature fluctuations on the rec-system was studied in this work. It is established that selection for population adaptability to extreme conditions leads during several tens of generations to significant increase in crossing-over rate within various parts of the genome (especially in b-cn and ru-h of chromosomes 2 and 3), as well as to relaxation of exchange interference for adjacent and non-adjacent segments. The Fisher's theoretical prognosis about tightening of linkage in optimal constant conditions was experimentally confirmed for the first time.
群体遗传学已经发展出了一些理论模型,用以解释在自然选择有利于适应性性状的情况下重组系统的进化。在这项研究中,利用大规模的果蝇笼养群体,研究了针对每日温度波动抗性的选择对重组系统的影响。研究发现,在几十代的时间里,选择使群体适应极端条件会导致基因组各部分的交叉率显著增加(特别是在2号和3号染色体的b-cn和ru-h区域),同时也会导致相邻和非相邻片段的交换干扰松弛。首次通过实验证实了费希尔关于在最佳恒定条件下连锁加强的理论预测。