在以铂类为基础的一线化疗结束十年后，再次使用卡铂治疗引发的超敏反应。
Hypersensitivity following Retreatment with Carboplatin a Decade after Completion of Primary Platinum-Based Chemotherapy.
作者信息
Williams Laura, Markman Maurie
机构信息
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tenn., USA.
出版信息
Case Rep Oncol. 2009 Feb 20;2(1):20-23. doi: 10.1159/000203358.
Abstract
The relatively rapid development of a platinum-associated hypersensitivity reaction in an ovarian cancer patient receiving second-line chemotherapy more than a decade following her last course of primary platinum-based chemotherapy demonstrates that the prolonged persistence of immune cells recognizing platinum after sensitization has been established.
摘要
一名卵巢癌患者在接受最后一个疗程的一线铂类化疗十多年后接受二线化疗时，相对迅速地出现了铂相关超敏反应，这表明致敏后识别铂的免疫细胞会长期持续存在。
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