多氯三联苯（PCT）对ICR小鼠的肝致癌性及其被六氯苯（HCB）增强的作用
Hepatocarcinogenicity of polychlorinated terphenyl (PCT) in ICR mice and its enhancement by hexachlorobenzene (HCB).
作者信息
Shirai T, Miyata Y, Nakanishi K, Murasaki G, Ito N
出版信息
Cancer Lett. 1978 May;4(5):271-5. doi: 10.1016/s0304-3835(78)95117-0.
PMID:207412
Abstract
Studies were made on the carcinogenic effects of hexachlorobenzene (HCB) and polychlorinated terphenyl (PCT) singly and in combination when given orally to mice for 24 weeks. PCT alone induced liver tumors, nodular hyperplasias and hepatocellular carcinomas. HCB alone had no effect, but it enhanced the induction of liver tumors by PCT.
摘要
对六氯苯（HCB）和多氯三联苯（PCT）单独及联合口服给予小鼠24周后的致癌作用进行了研究。单独使用PCT可诱发肝肿瘤、结节性增生和肝细胞癌。单独使用HCB没有效果，但它增强了PCT对肝肿瘤的诱发作用。
Zotero 插件