Kanda F, Jinnai K, Tada K, Fujita T
Department of Medicine, Kobe University School of Medicine, Japan.
Kidney Int. 1990 Dec;38(6):1085-8. doi: 10.1038/ki.1990.316.
Effects of acute renal failure (ARF) on somatosensory evoked potentials (SEP) were studied in rats. Cervical and cortical SEPs were measured both before and after bilateral ureteral ligation. A significant augmentation of amplitudes and an increase in latencies of the cortical SEP were observed in ARF. The peripheral nerve conduction velocities were unchanged. Serum parathyroid hormone (PTH) levels in uremic rats were significantly elevated after the bilateral ureteral ligation. In previously parathyroidectomized rats, the bilateral ureteral ligation had no effects on amplitudes of SEP or serum PTH levels.
研究了急性肾衰竭(ARF)对大鼠体感诱发电位(SEP)的影响。在双侧输尿管结扎前后分别测量了颈部和皮质SEP。在急性肾衰竭中观察到皮质SEP的波幅显著增大且潜伏期延长。周围神经传导速度未改变。双侧输尿管结扎后,尿毒症大鼠的血清甲状旁腺激素(PTH)水平显著升高。在先前已行甲状旁腺切除术的大鼠中,双侧输尿管结扎对SEP波幅或血清PTH水平没有影响。