Bucci E, Mignogna M D, Scaricabarozzi I, Bucci P, Lo Muzio L, Trezzani R
Istituto di Discipline Odontostomatologiche, Università degli Studi di Napoli, II Facoltà di Medicina e Chirurgia.
Minerva Stomatol. 1990 Oct;39(10):827-31.
A double-blind versus placebo clinical study has been carried out in order to assess the antiinflammatory and analgesic activity of nimesulide suppositories in pain-inflammatory pathologies of odontostomatological nature. Forty-four patients aged between 18 and 62 were recruited for the purpose and assigned at random to treatment with nimesulide or placebo for a minimum period of 3 days. Treatment with nimesulide reduced both the pain and the tumefaction due to the inflammatory pathology more rapidly and, by the 3rd day of treatment led to complete remission of the symptomatology. Tolerability of nimesulide was excellent.
为评估尼美舒利栓剂在牙口颌面部疼痛性炎症病变中的抗炎和镇痛活性，开展了一项双盲对照安慰剂临床研究。为此招募了44名年龄在18至62岁之间的患者，并将他们随机分配接受尼美舒利或安慰剂治疗，最短治疗期为3天。尼美舒利治疗能更快减轻炎症病变引起的疼痛和肿胀，到治疗第3天时症状完全缓解。尼美舒利的耐受性良好。
