Hinds L A
CSIRO Division of Wildlife and Ecology, Lyneham, Australia.
Reprod Fertil Dev. 1990;2(5):535-52. doi: 10.1071/rd9900535.
In most eutherian species the function of the corpus luteum (CL) is influenced by extrinsic factors and it is subordinate to the pituitary, placenta, or uterus. In contrast, in marsupials the CL is relatively autonomous. Although the pituitary is essential for the formation of the CL, thereafter the secretory activity of the CL is independent of luteotrophic support, and the uterus is not luteolytic. Furthermore, the life span of the CL is unaffected by pregnancy, except in the Macropodidae (kangaroos and wallabies), in which the secretory activity of the CL is shortened under the influence of the fetus. At parturition the macropodid fetus, possibly via a release of glucocorticoids, causes the release of prostaglandins, presumed to be of uterine origin. The effect of the prostaglandin is to induce the release of prolactin from the maternal pituitary. Prolactin, and not prostaglandin, induces luteolysis and advances the events of post-partum oestrus. In the non-pregnant cycle, the mechanism of luteolysis is different; it does not involve prolactin, and the luteolytic signal is of non-uterine, possibly intrinsic, origin.
在大多数真兽类物种中，黄体（CL）的功能受外在因素影响，且从属于垂体、胎盘或子宫。相比之下，有袋类动物的黄体相对自主。虽然垂体对黄体的形成至关重要，但此后黄体的分泌活动独立于促黄体支持，且子宫不具有溶黄体作用。此外，黄体的寿命不受妊娠影响，除了大袋鼠科（袋鼠和沙袋鼠），在该科动物中，黄体的分泌活动在胎儿的影响下会缩短。分娩时，大袋鼠科胎儿可能通过释放糖皮质激素，促使前列腺素释放，推测前列腺素源自子宫。前列腺素的作用是诱导母体垂体释放催乳素。催乳素而非前列腺素诱导黄体溶解并促进产后发情事件。在非妊娠周期中，黄体溶解机制不同；它不涉及催乳素，且溶黄体信号源自非子宫，可能是内在的。
