Vodovozov A M, Varnovitskiĭ A M
Vestn Oftalmol. 1990 Nov-Dec;106(6):40-2.
Examination of ocular constant potentials and darkness adaptation in the patients taking glycerol ascorbate has revealed that this hypotensive agent depressed the constant potentials in normal subjects, this manifesting by a drastic reduction of its darkness and light reaction. Simultaneous studies of darkness adaptation have shown it to be but slightly elevated or unchanged. The authors suppose that hyperosmotic stress induced by glycerol ascorbate involves the pigmented epithelium, a constant potential generator.
对服用甘油抗坏血酸的患者进行眼恒定电位和暗适应检查发现,这种降压药会降低正常受试者的恒定电位,表现为其暗反应和光反应急剧降低。同时进行的暗适应研究表明,暗适应仅略有升高或无变化。作者推测,甘油抗坏血酸引起的高渗应激涉及色素上皮,即恒定电位的产生部位。