Khokhlov S E, Pakhomova E N, Bykov V L
Zh Mikrobiol Epidemiol Immunobiol. 1990 Oct(10):35-8.
In the electron-microscopic study of the interaction of neutrophil granulocytes with the fungal species C. albicans in the process of the formation of mycotic foci in mice under the conditions of cyclophosphamide-induced immunosuppression, mouse leukocytes have been found to retain their capacity for migration to the focus of inflammation and for the phagocytosis of fungal cells. At the same time the fungicidal activity of leukocytes is decreased, which is manifested by the prevalence of viable fungal cells with the partially digested cell wall in the cytoplasm of leukocytes.
在环磷酰胺诱导免疫抑制条件下，对小鼠霉菌性病灶形成过程中嗜中性粒细胞与白色念珠菌之间相互作用的电子显微镜研究发现，小鼠白细胞仍保留其向炎症病灶迁移以及吞噬真菌细胞的能力。与此同时，白细胞的杀菌活性降低，这表现为白细胞胞质中存在具有部分消化细胞壁的存活真菌细胞。
