Fujimura I, de Carvalho C A, Rodrigues Júnior A J
Department of Anatomy, Biomedical Sciences Institute, University of São Paulo, Brazil.
Acta Anat (Basel). 1990;139(4):374-9. doi: 10.1159/000147026.
Based on our previous studies on the human normal venous angioarchitecture of the esophagogastric transition segment, we performed a similar analysis in 25 postmortem specimens obtained from subjects with a diagnosis of portal hypertension. The specimens were injected with India ink or barium sulfate and sectioned for histological examination. A 'weak' zone (point of lesser resistance) was described as being the most probable site of origin for the development of varicosities in the complex venous system of the esophagogastric junction. Such a system can be considered to be a physiological hemodynamic venous blockade mechanism interposed between the portal system and the systemic veins. The 'weak' zone is made up by the scarce submucous veins (shunt veins), by the submucous confluent and final confluent trunks, and by the true perforating veins of the tunica muscularis which compose a venous unity located about 3-5.5 cm above the Z (epithelioglandular) line.
基于我们之前对食管胃过渡段人类正常静脉血管结构的研究，我们对25例诊断为门静脉高压症患者的尸检标本进行了类似分析。标本用印度墨水或硫酸钡灌注，并切片进行组织学检查。“薄弱”区域（阻力较小的部位）被描述为食管胃交界处复杂静脉系统中静脉曲张形成的最可能起源部位。这样一个系统可被视为介于门静脉系统和体静脉之间的一种生理性血流动力学静脉阻断机制。“薄弱”区域由稀少的黏膜下静脉（分流静脉）、黏膜下汇合静脉和终末汇合静脉主干，以及肌层的真正穿通静脉组成，这些构成了一个位于Z（上皮腺）线以上约3 - 5.5厘米处的静脉整体。
