对一名怀孕的非霍奇金淋巴瘤患者进行的成功化疗。

Successful chemotherapy on a pregnant non-Hodgkin's lymphoma patient.

作者信息

Toki H, Okabe K, Kamei H, Shimokawa T, Hiura M, Kondo M, Hirota Y

机构信息

Department of Medicine, Shikoku Cancer Center Hospital, Japan.

出版信息

Acta Med Okayama. 1990 Dec;44(6):321-3. doi: 10.18926/AMO/30428.

DOI:10.18926/AMO/30428

PMID:2075830

Abstract

We report a case of a non-Hodgkin's lymphoma (NHL) patient treated successfully with combination chemotherapy during pregnancy who delivered a full-term baby. A 29 year-old patient with cervical and inguinal lymphadenopathy in the 27th week of gestation was referred to our hospital. The diagnosis of lymph node biopsy was NHL (diffuse, large cell type with B-cell phenotype). Three courses of CHOP regimen (adriamycin, cyclophosphamide, vincristine and prednisolone) were given before delivery. The patient has been in complete remission for three years and her baby has been in normal development. Our case supports previous reports that chemotherapy in the third trimester may be given safely on NHL patients.

摘要

我们报告一例非霍奇金淋巴瘤（NHL）患者，其在孕期接受联合化疗并成功产下一名足月婴儿。一名29岁患者在妊娠第27周时出现颈部和腹股沟淋巴结肿大，被转诊至我院。淋巴结活检诊断为NHL（弥漫性大细胞型，B细胞表型）。在分娩前给予了三个疗程的CHOP方案（阿霉素、环磷酰胺、长春新碱和泼尼松龙）。患者已完全缓解三年，其婴儿发育正常。我们的病例支持先前的报道，即妊娠晚期可对NHL患者安全进行化疗。