Structural proteins of infectious bovine rhinotracheitis virus.

Infectious bovine rhinotracheitis (IBR) virus grown in bovine embryo kidney cell cultures was concentrated and purified in Ficoll density gradients. The polypeptide composition of the virus was studied by polyacrylamide gel electrophoresis. The mature virion was found to contain 18 structural proteins with molecular weights from 250,000 to 29,000 daltons; 8 of them were glycosylated. The similarity of IBR virus protein composition to proteins of other herpetoviruses is discussed.