Rins de David M L, Caceres A, Goldraij A
Universidad de Córdoba e I.N.I.M.E.C. (CONICET), Argentina.
Acta Odontol Latinoam. 1990;5(1):63-9.
The existence of sexual dimorphism (SDM) in tubules and acini of the submaxillary gland was investigated in male and female 60 day-old Wistar rats. Conventional histology was followed by evaluation of 1) Percentage of area occupied by tubules, acini, and other tissues and 2) Tubular area, employing a semi-automatic image analyser. The granular tubules of male rats were larger than those of females. This statistically significant difference indicates the existence of SDM from a morphological viewpoint. Castration seems to abolish these differences by inducing involution of tubular tissue in males. Whereas treatment with testosterone seems to reconstitute tubular tissue in castrated males, a similar dose of estradiol benzoate elicits a reduction in tubular size in ovariectomized females.
在60日龄的雄性和雌性Wistar大鼠中，研究了下颌下腺小管和腺泡中的性二态性（SDM）。采用传统组织学方法，随后使用半自动图像分析仪评估：1）小管、腺泡和其他组织所占面积的百分比；2）小管面积。雄性大鼠的颗粒小管比雌性大鼠的大。这一具有统计学意义的差异从形态学角度表明了性二态性的存在。阉割似乎通过诱导雄性大鼠管状组织退化来消除这些差异。而用睾酮治疗似乎能使阉割后的雄性大鼠的管状组织恢复，类似剂量的苯甲酸雌二醇会使去卵巢雌性大鼠的小管尺寸减小。
