Cadmium induced changes in the liver of langurs (Presbytis entellus-entellus dufresne).

1- Cadmium-induced hepatic disturbances in Langurs have been studied following a single low dose administration of the salt (Cd Cl2 4 mg/kg s.c.). 2-Serum transaminases, choelsterol and liver glycogen levels were elevated. Alkaline phosphatase levels were in normal range. The blood sugar was at a low level. 3- Degranulation, vacuolization and distortion of the liver cells and lobules were conspicuous. 4- In conclusion this study would indicate that increased serum enzyme activity and increased plasma choelsterol levels are a manifestation of tissue damage. It would seem plausible to translate these observations in terms of similar infarcts occurring in man.