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Use of benzoctamine as sedative in patients with respiratory failure.

作者信息

Clark T J, Collins J V

出版信息

Br Med J. 1973 Jan 13;1(5845):75-6. doi: 10.1136/bmj.1.5845.75.

Abstract

Benzoctamine (Tacitin) was given by mouth as night sedation to patients admitted to hospital with respiratory failure. Fourteen patients had chronic obstructive bronchitis and six had acute severe asthma. One patient with asthma needed intravenous sedation with benzoctamine. No adverse effects were observed, and there was no significant change of forced expiratory volume in one second (FEV(1)), forced vital capacity (FVC), or Pco(2) in any patient after benzoctamine. Nevertheless, further clinical experience of the drug is required before its use can be safely recommended in respiratory failure.

摘要

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本文引用的文献

1
USE OF SEDATIVES, RELAXANTS, AND RESPIRATORY STIMULANTS IN RESPIRATORY FAILURE.
Ann N Y Acad Sci. 1965 Mar 24;121:836-48. doi: 10.1111/j.1749-6632.1965.tb14253.x.
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Rebreathing method for measurement of mixed venous PCO2.
Br Med J. 1962 Sep 8;2(5305):630-3. doi: 10.1136/bmj.2.5305.630.
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Respiratory depression caused by nitrazepam in patients with respiratory failure.
Lancet. 1971 Oct 2;2(7727):737-8. doi: 10.1016/s0140-6736(71)92105-2.

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